Serrapeptase

"Its distinctive feature is that its affinity is not just to proteins but specifically to non-living proteins."

But first, an update on Iodine for Horses, Scratches. Jack’s scratches appear to be totally healed after a few months on iodine-containing Focus HF, and a couple of weeks of occasional topical treatment with MTG - mineral oil with elemental sulfur mixed in. After many years of unsuccessful Rx vet topical treatments. And even oral antibiotics at one point.

And now, Tessa Lena’s fantastic article about serrapeptase. I’ve been taking it to get rid of some nasty slime at the back of my throat, and it helped on the first day. I’m about to make up some nose spray and gargle with contents of a capsule in distilled water, maybe get rid of the rest of the slime. I also recommend serrapeptase or nattokinase or lumbrokinase to my friends and family who worry about atherosclerosis and heart disease.

And look! A product for horses!

https://www.steelhorseformulations.com/buy-serraquin

Now Tessa:

Sweeping the Body: Meet Serrapeptase Enzyme

Does anyone here not know about biofilms? Discuss in the comments if you don’t. It is key info for many chronic things. Like back of the throat slime. Here’s Tessa:

Antibiofilm activity

In biofilms [a “slimy” protective layer formed by colonies of pathogenic organisms such as bacteria or fungi, including in the gut], serrapeptase can alter the pathogenic phenotype of a pathogen. Serrapeptase, a proteolytic enzyme, was originally suggested by Selan et al. for the treatment of biofilm-related illnesses nearly twenty years ago.32

Another observation regarding the serrapeptase enzyme based on its anti-biofilm activity was against a fully matured Staphylococcus aureus biofilm. Serrapeptase is known to exhibit the property of modifying the adhesion molecules and thereby reducing the cell surface proteins.33 Selan et al. reported that the enzyme could alter the biofilm association of virulent strains, and that it showed activity against a completely developed biofilm.34

Biofilms are normally difficult to destroy. Serrapeptase, in combination with other antibiotics, exhibited potent anti-bioflim activity. The serrapeptase enzyme has reduced the expression of Listeria monocytogens cell surface proteins such as Ami4b, internalin B, Act A, and autolysin. The enzyme significantly precluded the adhesion of Listeria monocytogens in the human digestive tract. 35 According to previous reports, it was found that the enzyme has the ability to interact only with the cell adhesion molecules that formed the biofilm. No cytotoxic activity was recorded. It can act on these surface proteins by altering adhesins and autolysins. In a study reported by Artini et al., it was stated that serrapeptase and carboxypeptidase showed activity against biofilm formation of different strains of Staphylococcus aureus and Staphylococcus epidermidis. The test results of the previous studies showed that only serrapeptase inhibited the activity of all strains. The enzyme has the ability to modify the phenotype of virulent bacteria and enhance anti-bacterial properties. 36